Age-Adjusted Survival Extrapolations-Results May Differ From Those Generated by the Weibull Model
Messori A., Mengato D., Chiumente M.
Analisi statistiche e metanalisi
To the Editor In analyzing a clinical trial, extrapolating survival curves beyond the length of the follow-up is an option that, for many years, has attracted the interest of researchers. For example, when 2 treatments are being compared, this extrapolation provides a useful estimate of the survival gain in the long term or even in a lifetime perspective. The Weibull model is the one most commonly used for this purpose.1 One advantage of this model is that a number of standard statistical software (including the R platform [The R Foundation]) implement and facilitate its application.
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